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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12103960 B1

PDFFull Text
Date of Patent:
Oct. 01, 2024

Filed:

May. 07, 2021

Vegf traps and mini-traps and methods for treating ocular disorders and cancer

Applicant:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Inventors:

William Olson, Yorktown Heights, NY (US);

Joel Martin, Putnam Valley, NY (US);

Neil Stahl, Carmel, NY (US);

Jee Kim, Ardsley, NY (US);

Assignee:

REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);

Attorney:

Troutman Pepper Hamilton Sanders LLP

Primary Examiner:

Julie Ha

Int. Cl.
CPC ...
C07K 14/71 (2006.01); A61K 38/00 (2006.01); A61P 27/02 (2006.01); A61P 27/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); A61P 27/02 (2018.01); A61K 38/00 (2013.01); C07K 2317/53 (2013.01);
Abstract

Vascular endothelial growth factor (VEGF) traps and VEGF mini-traps that include VEGF receptor Ig-like domains, fused to a multimerizing component, are disclosed. The VEGF traps and VEGF mini-traps bind to VEGF and block its interaction with the VEGF receptor. Such molecules are useful for treating angiogenic eye disorders (e.g., age-related macular degeneration), cancer and for other undesired angiogenesis.

Find Patent Forward Citations

Olson, William. (2024). Vegf traps and mini-traps and methods for treating ocular disorders and cancer (U.S. Patent No. 12103960). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12103960

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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