The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2024
Filed:
May. 07, 2021
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventors:
William Olson, Yorktown Heights, NY (US);
Joel Martin, Putnam Valley, NY (US);
Neil Stahl, Carmel, NY (US);
Jee Kim, Ardsley, NY (US);
Assignee:
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/71 (2006.01); A61K 38/00 (2006.01); A61P 27/02 (2006.01); A61P 27/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); A61P 27/02 (2018.01); A61K 38/00 (2013.01); C07K 2317/53 (2013.01);
Abstract
Vascular endothelial growth factor (VEGF) traps and VEGF mini-traps that include VEGF receptor Ig-like domains, fused to a multimerizing component, are disclosed. The VEGF traps and VEGF mini-traps bind to VEGF and block its interaction with the VEGF receptor. Such molecules are useful for treating angiogenic eye disorders (e.g., age-related macular degeneration), cancer and for other undesired angiogenesis.