The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2024

Filed:

May. 02, 2019
Applicant:

Acceleron Pharma Inc., Cambridge, MA (US);

Inventors:

Ravindra Kumar, Acton, MA (US);

Dianne S. Sako, Medford, MA (US);

Roselyne Castonguay, Watertown, MA (US);

Tzu-Hsing Kuo, Chestnut Hill, MA (US);

Assignee:

ACCELERON PHARMA INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 38/00 (2006.01); C07K 14/71 (2006.01); C07K 16/22 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70578 (2013.01); C07K 14/71 (2013.01); C07K 16/22 (2013.01); A61K 38/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01);
Abstract

In certain aspects, the disclosure provides multispecific binders (e.g., ActRIIA:TβRII heteromultimers comprising an ActRIIA polypeptide and a TβRII polypeptide). The disclosure further provides that such multispecific binders (e.g., ActRIIA:TβRII heteromultimer) may be used to treat various disorders or conditions.


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