The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2024

Filed:

Nov. 16, 2020
Applicants:

Korea Institute of Ocean Science & Technology, Busan, KR;

Kiweon Cha, Cheongju-si, KR;

Inventors:

Jung-Hyun Lee, Busan, KR;

Hyung-Soon Yim, Seoul, KR;

Young Jun An, Ansan-si, KR;

Kyeong Won Lee, Busan, KR;

Ye Eun Jeong, Busan, KR;

Kiweon Cha, Cheongju-si, KR;

Won Kyu Lee, Goyang-si, KR;

Jurang Woo, Sejong, KR;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/50 (2006.01); C12N 5/0735 (2010.01);
U.S. Cl.
CPC ...
C07K 14/50 (2013.01); C12N 5/0606 (2013.01);
Abstract

Provided is a polypeptide having FGF2 activity and improved temperature stability and protease resistance. The polypeptide includes at least one substitution selected from a substitution of aspartic acid (D) with glutamic acid (E) at position 28, a substitution of cysteine (C) with isoleucine (I) or leucine (L) at position 78, or a substitution of cysteine (C) with isoleucine (I) or tryptophan (W) at position 96 in SEQ ID NO: 1.


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