The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2024
Filed:
Mar. 19, 2021
Applicants:
Duke University, Durham, NC (US);
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Inventors:
Pei Zhou, Durham, NC (US);
Eric J. Toone, Durham, NC (US);
Robert A. Nicholas, Chapel Hill, NC (US);
Ramesh Gopalaswamy, Durham, NC (US);
Xiaofei Liang, Durham, NC (US);
Frank Navas, III, Durham, NC (US);
Assignees:
Duke University, Durham, NC (US);
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 259/06 (2006.01); A61P 31/04 (2006.01); C07C 237/34 (2006.01); C07C 259/18 (2006.01); C07C 311/06 (2006.01); C07C 317/18 (2006.01); C07C 317/44 (2006.01); C07D 203/08 (2006.01); C07D 203/18 (2006.01); C07D 207/327 (2006.01); C07D 213/64 (2006.01); C07D 263/16 (2006.01); C07D 265/30 (2006.01); C07D 277/40 (2006.01); C07D 295/10 (2006.01); C07D 295/155 (2006.01); C07D 309/04 (2006.01); C07D 309/10 (2006.01); C07D 335/02 (2006.01); C07H 15/203 (2006.01);
U.S. Cl.
CPC ...
C07C 259/06 (2013.01); A61P 31/04 (2018.01); C07C 237/34 (2013.01); C07C 259/18 (2013.01); C07C 311/06 (2013.01); C07C 317/18 (2013.01); C07C 317/44 (2013.01); C07D 203/08 (2013.01); C07D 203/18 (2013.01); C07D 207/327 (2013.01); C07D 213/64 (2013.01); C07D 263/16 (2013.01); C07D 265/30 (2013.01); C07D 277/40 (2013.01); C07D 295/10 (2013.01); C07D 295/155 (2013.01); C07D 309/04 (2013.01); C07D 309/10 (2013.01); C07D 335/02 (2013.01); C07H 15/203 (2013.01); C07C 2601/02 (2017.05); C07C 2601/08 (2017.05); C07C 2601/14 (2017.05);
Abstract
Disclosed are compounds of formulae: and pharmaceutically acceptable salts thereof, wherein the variables, R, R, R, R, R, R, R, R, R, R, R, R, R, R, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.