Treatment and planning for lymphocytes sparing radiotherapy

Abstract

The present document relates to providing a radiation treatment plan for treatment of a neoplasm, including the steps of: obtaining an image including the neoplasm and obtaining first segmentation data for segmenting at least one target-volume to be targeted with radiation. Further identifying any organs-at-risk and segmenting these. The method further comprises identifying lymphocyte-rich-organs in the image, and obtaining third segmentation data for segmenting the lymphocyte-rich-organs. The planning system then obtains radiation dose regime data, including first, second and third dose regime data. The planning system then determines a radiation treatment plan which provides treatment process parameters for operating one or more radiation beams for radiation treatment of the neoplasm, The process parameters are determined to apply the radiation at a first radiation dose to the target volume which corresponds with the first dose regime data, apply the radiation at a minimized second radiation dose to the or each organs-at-risk, and apply the radiation at a third radiation dose to the or each lymphocyte-rich-organ which corresponds with the third dose regime data, wherein the third radiation dose amount is minimized.