The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2024

Filed:

Nov. 22, 2021
Applicant:

Verily Life Sciences Llc, South San Francisco, CA (US);

Inventors:

Kimberly Kam, Orinda, CA (US);

Zhan Wang, San Jose, CA (US);

Stephen Morton, Mountain View, CA (US);

Nicole Peck, Redwood City, CA (US);

Assignee:

VERILY LIFE SCIENCES LLC, South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 31/7088 (2006.01); A61K 38/02 (2006.01); A61K 39/395 (2006.01); A61K 47/42 (2017.01); A61K 47/69 (2017.01); A61K 49/00 (2006.01); A61P 39/06 (2006.01); B01J 13/22 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1271 (2013.01); A61K 9/1277 (2013.01); A61K 31/7088 (2013.01); A61K 38/02 (2013.01); A61K 39/395 (2013.01); A61K 47/42 (2013.01); A61K 47/6913 (2017.08); A61K 49/0032 (2013.01); A61K 49/0086 (2013.01); A61P 39/06 (2018.01); B01J 13/22 (2013.01); Y10S 977/773 (2013.01); Y10S 977/906 (2013.01); Y10S 977/907 (2013.01);
Abstract

Provided herein are encapsulated liposomes comprising a lipid bilayer, a first polyethylene glycol (PEG) corona, a targeting molecule and a second PEG corona. The second, encapsulating PEG corona can be reversibly linked to the first PEG corona. Also provided are pharmaceutical compositions comprising the encapsulated liposomes and methods of treating a subject with a disease characterized by production of reactive oxygen species (ROS) with the compositions. Also provided are methods of making the encapsulated liposomes disclosed herein.


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