The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2024

Filed:

Dec. 05, 2023
Applicant:

Auson Pharmaceuticals, Inc., Bridgewater, NJ (US);

Inventors:

Peng Hou, Shanghai, CN;

Enxian Lu, East Brunswick, NJ (US);

Longlong Feng, Shanghai, CN;

Assignee:

AUSON PHARMACEUTICALS INC., Bridgewater, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/38 (2006.01); A61K 9/06 (2006.01); A61K 31/554 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/32 (2006.01);
U.S. Cl.
CPC ...
A61K 47/38 (2013.01); A61K 9/06 (2013.01); A61K 31/554 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/32 (2013.01);
Abstract

The present invention provides a pharmaceutical composition of diltiazem hydrochloride. The pharmaceutical composition is preferably a gel and consists of diltiazem hydrochloride and excipients including propylene glycol, benzoic acid, and a gel matrix, which is one of or a mixture of povidone and hydroxypropyl cellulose. Based on percentage by weight, the diltiazem hydrochloride accounts for 1%-5%, the benzoic acid accounts for 0.1%-5.0%, the gel matrix accounts for 5%-10%, and the balance is propylene glycol, with pH maintained at 3.0-4.5. A preparation method is provided accordingly, with simple and readily available raw materials and stable quality.


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