The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2024
Filed:
Aug. 21, 2023
Applicant:
Centre for Virology, Vaccinology and Therapeutics Limited, Hong Kong, CN;
Inventors:
Assignee:
Centre for Virology, Vaccinology and Therapeutics Limited, Hong Kong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2006.01); A61K 9/00 (2006.01); A61P 31/14 (2006.01); C07K 14/165 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/215 (2013.01); A61K 9/0043 (2013.01); A61P 31/14 (2018.01); C07K 14/165 (2013.01); A61K 2039/543 (2013.01); A61K 2039/545 (2013.01);
Abstract
The present application provides chimeric proteins comprising comprising a receptor binding domain ('RBD') of a SARS-CoV-2 spike protein (“S protein”) fused to a booster enhancer domain (“BED”) and uses thereof as vaccine or vaccine booster compositions. Also provided are method of boostering SARS-CoV-2 vaccines by administering to a vaccinated individual an effective amount of the vaccine booster composition, wherein the vaccine booster composition comprises a spike protein or a fragment thereof, and optionally wherein the vaccine booster composition is administered intranasally.