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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12102672 B1

PDFFull Text
Date of Patent:
Oct. 01, 2024

Filed:

Dec. 21, 2018

Immunogenic sequences from a phage tail length tape measure protein, bacteria expressing the same and their use in treating a cancer

Applicants:

Institut Gustave Roussy, Villejuif, FR;

Institut National DE LA Sante ET DE LA Recherche Medicale, Paris, FR;

Universite Paris-saclay, Gif Sur Yvette, FR;

Centre Hospitalier Universitaire DE Rennes, Rennes, FR;

Universite DE Rennes, Rennes, FR;

Inventor:

Laurence Zitvogel, Paris, FR;

Assignees:

INSTITUT GUSTAVE ROUSSY, Villejuif, FR;

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, Paris, FR;

UNIVERSITE PARIS-SACLAY, Gif Sur Yvette, FR;

CENTRE HOSPITALIER UNIVERSITAIRE DE RENNES, Rennes, FR;

UNIVERSITE DE RENNES, Rennes, FR;

Attorney:

Arrigo, Lee, Guttman & Mouta-Bellum LLP

Primary Examiner:

Sean E Aeder

Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 35/76 (2015.01); A61K 45/00 (2006.01); A61P 35/00 (2006.01); C07K 14/005 (2006.01); C07K 14/74 (2006.01); C12N 5/0783 (2010.01); C12N 15/74 (2006.01); C12Q 1/02 (2006.01); C12Q 1/6886 (2018.01); G01N 33/50 (2006.01); G01N 33/543 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 35/76 (2013.01); A61K 45/00 (2013.01); A61P 35/00 (2018.01); C07K 14/005 (2013.01); C07K 14/70539 (2013.01); C12N 5/0636 (2013.01); C12N 15/746 (2013.01); C12Q 1/025 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5091 (2013.01); G01N 33/54306 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/523 (2013.01); C12N 2509/00 (2013.01); C12N 2795/10321 (2013.01); C12N 2795/10333 (2013.01); C12N 2795/10343 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention relates to the field of probiotic adjuvantization of anticancer treatments. In particular, the present invention concerns immunogenic sequences from a prophage present in bacteria identified as efficient adjuvants of cancer treatments. The invention provides bacterial compositions expressing immunogenic sequences from this prophage, immunogenic compositions comprising such sequences and methods using sequences from this prophage, for increasing the anticancer armamentarium.

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