The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2024

Filed:

Jul. 18, 2019
Applicant:

Korea University Research and Business Foundation, Seoul, KR;

Inventors:

Sung Hoi Hong, Seoul, KR;

Kyung-Ah Choi, Cheorwon-gun, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/57 (2006.01); A61K 35/30 (2015.01); A61K 35/545 (2015.01);
U.S. Cl.
CPC ...
A61K 38/57 (2013.01); A61K 35/30 (2013.01); A61K 35/545 (2013.01);
Abstract

The present invention relates to a composition for inhibiting teratoma formation or growth, comprising tissue inhibitor of metalloproteinase 1 (TIMP-1) or tissue inhibitor of metalloproteinase 2 (TIMP-2) as an effective component. A pharmaceutical composition for inhibiting teratoma formation or growth comprising TIMP-1 or TIMP-2 as an effective component according to the present invention, when used in stem cell therapy, can inhibit the formation and growth of teratomas caused by undifferentiated pluripotent stem cells, without affecting the differentiation potential thereof, and thus can be advantageously used as a combination drug in combination with a stem cell drug.


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