The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2024
Filed:
Dec. 04, 2019
Applicant:
Viking Therapeutics, Inc., San Diego, CA (US);
Inventors:
Brian Lian, Rancho Santa Fe, CA (US);
Hiroko Masamune, San Diego, CA (US);
Geoffrey E. Barker, Carlsbad, CA (US);
Assignee:
Viking Therapeutics, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/662 (2006.01); A61K 31/665 (2006.01); A61P 1/16 (2006.01); A61P 11/00 (2006.01); A61P 17/02 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/662 (2013.01); A61K 31/665 (2013.01); A61P 1/16 (2018.01); A61P 11/00 (2018.01); A61P 17/02 (2018.01); A61P 29/00 (2018.01);
Abstract
The present disclosure is directed to methods of treating fibrotic conditions and inflammation by administration of TRβ agonists. The disclosure provides methods wherein the abnormal deposition of extracellular matrix components, such as collagen, keratin, or elastin, is reduced, either through interaction of TRβ agonists with TGF-β-dependent inflammatory pathways, or by other mechanisms, thereby ameliorating fibrotic symptoms.