The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
May. 31, 2019
Andre Bernard, St. Gallen, CH;
Peter Heeb, Balgach, CH;
Cornelia Nef, Gams, CH;
Dominik Obrist, Suhr, CH;
Francesco Clavica, Derendingen, CH;
Sabrina Frey, Bern, CH;
Robert S. Schwartz, Inver Grover Heights, MN (US);
Jon Helge Hoem, Baar, CH;
Oliver Bludau, Baar, CH;
Andre Bernard, St. Gallen, CH;
Peter Heeb, Balgach, CH;
Cornelia Nef, Gams, CH;
Dominik Obrist, Suhr, CH;
Francesco Clavica, Derendingen, CH;
Sabrina Frey, Bern, CH;
Robert S. Schwartz, Inver Grover Heights, MN (US);
Jon Helge Hoem, Baar, CH;
Oliver Bludau, Baar, CH;
CorFlow Therapeutics AG, Baar, CH;
Abstract
Systems, methods and apparatus are included that are configured to model microvascular obstruction (MVO) in patients. According to one aspect of the present disclosure, a multi-scale model is configured to mimic myocardial microcirculation of coronary vessels. The model includes collaterals configured to provide alternative pathways possibly bypassing the MVO, and configured to model coronary artery compliance for spatially resolved fluid transport through the coronary vessels. The model is configured to simulate the MVO by increasing flow resistance in at least one of the modelled coronary vessels, or by blocking the at least one of the modelled coronary vessels completely. The model is also configured to mimic behavior of fluid transport in the coronary vessels during diagnostics or treatment, to design and optimize therapy protocols for the MVO.