The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2024

Filed:

Feb. 03, 2020
Applicant:

Osaka University, Osaka, JP;

Inventors:

Kensuke Ikenaka, Osaka, JP;

Hideki Mochizuki, Osaka, JP;

Cesar Aguirre Martinez, Osaka, JP;

Yuji Goto, Osaka, JP;

Masatomo So, Osaka, JP;

Keita Kakuda, Osaka, JP;

Hirotsugu Ogi, Osaka, JP;

Kentaro Noi, Osaka, JP;

Assignee:

Osaka University, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); G01N 33/582 (2013.01); G01N 33/6845 (2013.01); G01N 2333/47 (2013.01); G01N 2800/2835 (2013.01);
Abstract

A method for discriminating between Parkinson's disease and multiple system atrophy, the method comprising the steps of: (1) preparing a solution containing α-synuclein monomers having a tendency to produce rod-like aggregates and/or a solution containing α-synuclein monomers having a tendency to produce twisted aggregates; (2) adding a biological sample from a subject to the solution(s) containing the α-synuclein monomers prepared in step (1); (3) allowing the α-synuclein monomers to aggregate in the solution(s) obtained in step (2); and (4) detecting α-synuclein aggregates formed in step (3).


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