The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
Jul. 07, 2023
Novo Nordisk A/s, Bagsvaerd, DK;
Andreas Vegge, Frederiksberg, DK;
Daniele Granata, Copenhagen, DK;
Jais Rose Bjelke, Smoerum, DK;
Jacob Lund, Roskilde, DK;
Philip Jonas Sassene, Copenhagen V, DK;
Per J. Greisen, Belmont, WA (US);
Thomas Egebjerg, Ganloese, DK;
Evelyn De Tavernier, Deurle, BE;
Soren Steffensen, Etterbeek, BE;
Marie-Ange Buyse, Merelbeke, BE;
Frantisek Hubalek, Herlev, DK;
Simone Fulle, Copenhagen, DK;
Mathias Norrman, Staffanstorp, SE;
Novo Nordisk A/S, Bagsvaerd, DK;
Abstract
The present invention provides ISVD polypeptide derivatives capable of binding coagulation Factor IX(a) and Factor X(a) which are highly potent and provide a sufficiently long half-life such to allow for effective subcutaneous—as well as peroral administration. The ISVD polypeptides derivatives disclosed herein are thus suitable for treatment of haemophilia A, haemophilia A with inhibitors and acquired haemophilia A by various routes of administration including subcutaneous and peroral administration.