The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
May. 05, 2022
Applicant:
Cepheid, Sunnyvale, CA (US);
Inventor:
Russell Higuchi, Alameda, CA (US);
Assignee:
CEPHEID, Sunnyvale, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12N 15/11 (2006.01); C12P 19/34 (2006.01); C12Q 1/6876 (2018.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); C12P 19/34 (2013.01); C12Q 1/6876 (2013.01); C12N 2310/321 (2013.01); C12N 2310/333 (2013.01); C12N 2310/334 (2013.01); C12N 2310/335 (2013.01); C12N 2310/336 (2013.01); C12N 2310/531 (2013.01);
Abstract
Described herein are methods and compositions that provide highly efficient nucleic acid amplification. In some embodiments, this allows a 3-fold or greater increase of amplification product for each amplification cycle and therefore increased sensitivity and speed over conventional PCR. Modified bases can be employed in primers to provide this base-3 or greater amplification with satisfactory PCR cycle times, which are improved, as compared to those observed in the absence of modified bases.