The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
May. 15, 2023
Applicants:
The General Hospital Corporation, Boston, MA (US);
Northeastern University, Boston, MA (US);
Inventors:
Hak Soo Choi, Needham, MA (US);
Jonghan Kim, Cambridge, MA (US);
Georges El Fakhri, Brookline, MA (US);
Assignees:
The General Hospital Corporation, Boston, MA (US);
Northeastern University, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C09B 23/01 (2006.01); C09B 69/10 (2006.01);
U.S. Cl.
CPC ...
C09B 23/0066 (2013.01); C09B 23/0025 (2013.01); C09B 23/0033 (2013.01); C09B 23/0041 (2013.01); C09B 69/105 (2013.01);
Abstract
Provided herein are compounds that are able to bind metal ions (e.g., free metal ions or metal ions bound to low affinity ligands) in a sample or subject. Also provided herein are methods of using the compounds for chelating metal ions and for the treatment of diseases associated with abnormal levels of metal ions. Methods of preparing the compounds and pharmaceutical compositions are also provided.