The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
Jun. 04, 2018
Applicant:
Numab Therapeutics Ag, Wädenswil, CH;
Inventors:
David Urech, Jona, CH;
Tea Gunde, Zurich, CH;
Sebastian Meyer, Eggenwil, CH;
Christian Hess, Zurich, CH;
Alexandre Simonin, Rosenau, FR;
Assignee:
Numab Therapeutics AG, Horgen, CH;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); C07K 16/32 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01); C07K 2317/64 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract
This invention relates to a hetero-dimeric multi-specific format of multiple antibody variable domains comprising a core of two split variable domain pairs wherein both variable light domains and the two cognate variable heavy domains are positioned in tandem on two separate protein chains, respectively, and wherein one of said variable domain pairs is specific for human serum albumin and the other said variable domain pair is specific for human CD3.