The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2024

Filed:

Jan. 03, 2018
Applicant:

Research Institute AT Nationwide Children's Hospital, Columbus, OH (US);

Inventors:

Lauren O. Bakaletz, Hilliard, OH (US);

Steven D. Goodman, Hilliard, OH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/12 (2006.01); A01N 63/50 (2020.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61P 31/04 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1203 (2013.01); A01N 63/50 (2020.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); C07K 16/1242 (2013.01); G01N 33/56911 (2013.01); A61K 2039/505 (2013.01); A61K 2039/52 (2013.01); C07K 2317/24 (2013.01); C07K 2317/55 (2013.01); C07K 2317/76 (2013.01); G01N 2333/285 (2013.01);
Abstract

This disclosure provides antibody fragments and isolated polypeptides comprising the antibody fragments that are useful as a therapeutic for those with an existing infection characterized by the formation of biofilms. Antibody fragments and isolated polypeptides comprising the antibody fragments can be administered to detect, treat, or prevent infection and/or remediate biofilms. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics.


Find Patent Forward Citations

Loading…