The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2024

Filed:

Oct. 25, 2019
Applicant:

Cellemedy Co., Ltd, Incheon, KR;

Inventors:

Jeewon Lee, Seoul, KR;

Bo Ram Lee, Seoul, KR;

Assignee:

CELLEMEDY CO., LTD, Incheon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); A61K 9/51 (2006.01); A61K 33/242 (2019.01); A61K 38/00 (2006.01); A61K 38/38 (2006.01); A61K 49/00 (2006.01); C07K 16/18 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 9/5169 (2013.01); A61K 9/5184 (2013.01); A61K 33/242 (2019.01); A61K 38/38 (2013.01); A61K 49/0056 (2013.01); A61K 49/0093 (2013.01); C07K 16/18 (2013.01); C12N 7/00 (2013.01); A61K 38/00 (2013.01); C07K 2319/31 (2013.01); C07K 2319/735 (2013.01); C12N 2710/10032 (2013.01); C12N 2730/10122 (2013.01); C12N 2730/10123 (2013.01);
Abstract

The present invention relates to recombinant self-assembling protein nanoparticles presenting an albumin-binding peptide at the surface. For the recombinant self-assembling protein nanoparticles according to the present invention, an albumin-binding peptide can reduce the immunogenicity of the recombinant self-assembling protein nanoparticles because the albumin-binding peptide is presented at the surface, and thus binds to an albumin protein present in vivo, and the albumin-binding peptide can also provide the cancer delivery function of the recombinant self-assembling protein nanoparticles because the albumin-binding peptide binds to albumin around cancer. Simultaneously, the binding of the albumin-binding peptide to albumin can significantly increase the in vivo residence time of the recombinant self-assembling protein nanoparticles, thus increasing the potential for use in various medical applications.


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