The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
Sep. 30, 2022
National University Corporation Hokkaido University, Hokkaido, JP;
Shionogi & Co., Ltd., Osaka, JP;
Akihiro Ishii, Hokkaido, JP;
Akihiko Sato, Hokkaido, JP;
Makoto Kawai, Osaka, JP;
Yoshiyuki Taoda, Osaka, JP;
NATIONAL UNIVERSITY COPORATION HOKKAIDO UNIVERSITY, Hokkaido, JP;
SHIONOGI & CO., LTD., Osaka, JP;
Abstract
The present invention provides a compound having antiviral activity, especially having arenavirus proliferation inhibitory activity, and/or a medicament comprising the compound. More preferably, the present invention provides a compound having proliferation inhibitory activity on the Old World arenaviruses such as Luna virus, Lassa virus, and lymphocytic choriomeningitis virus and/or the New World arenaviruses such as Junin virus, and/or a medicament comprising the compound. An arenavirus proliferation inhibitor comprising a compound represented by Formula (I) or a prodrug thereof or a pharmaceutically acceptable salt thereof: (wherein Ris carboxy, or the like: Ais CRor N; Ris a hydrogen atom, halogen, hydroxy, or the like; Ris a hydrogen atom, hydroxy, carboxy, cyano, formyl, alkyl optionally substituted with Substituent group F, or the like; either Aor Ais CRR, and the other is NR, or Ais CRR, and Ais CROR; and R, R, R, R, R, R, and Rare each independently a hydrogen atom, carboxy, cyano, alkyl optionally substituted with Substituent group F, or the like).