The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
Aug. 22, 2022
Applicants:
Versitech Limited, Hong Kong, CN;
Laboratory for Synthetic Chemistry and Chemical Biology Limited, Hong Kong, CN;
Inventors:
Chi-Ming Che, Hong Kong, CN;
Tingjie You, Hong Kong, CN;
Assignees:
VERSITECH LIMITED, Hong Kong, CN;
LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LIMITED, Hong Kong, CN;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 207/06 (2006.01); B01J 31/22 (2006.01); C07D 207/12 (2006.01); C07D 207/14 (2006.01); C07D 217/26 (2006.01); C07D 221/22 (2006.01); C07D 223/18 (2006.01); C07D 233/32 (2006.01); C07D 401/04 (2006.01); C07D 403/10 (2006.01); C07D 405/04 (2006.01); C07D 417/04 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 487/22 (2006.01);
U.S. Cl.
CPC ...
C07D 207/06 (2013.01); B01J 31/2295 (2013.01); C07D 207/12 (2013.01); C07D 207/14 (2013.01); C07D 217/26 (2013.01); C07D 221/22 (2013.01); C07D 223/18 (2013.01); C07D 233/32 (2013.01); C07D 401/04 (2013.01); C07D 403/10 (2013.01); C07D 405/04 (2013.01); C07D 417/04 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 487/22 (2013.01);
Abstract
Described herein is an iron(II)-phthalocyanine catalyzed C—H bond amination of alkyl azides. The catalyst is effective to produce intramolecular amination of saturated C—H bonds in moderate to excellent yields and the methods are tolerant of a wide scope of substrates. The methods described are useful for the synthesis of natural products derivatives and for the late-stage functionalization of pharmaceuticals.