The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2024

Filed:

May. 14, 2018
Applicant:

Nutshell Biotech (Shanghai) Co., Ltd., Shanghai, CN;

Inventors:

Jian Zhang, Shanghai, CN;

Yinyi Chen, Shanghai, CN;

Cong Ruan, Shanghai, CN;

Xiuyan Yang, Shanghai, CN;

Chengxiang Wang, Shanghai, CN;

Qiufen Zhang, Shanghai, CN;

Jialin Shang, Shanghai, CN;

Xinyuan Xu, Shanghai, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 303/38 (2006.01); C07C 311/37 (2006.01); C07C 311/44 (2006.01);
U.S. Cl.
CPC ...
C07C 303/38 (2013.01); C07C 311/37 (2013.01); C07C 311/44 (2013.01);
Abstract

Disclosed by the present invention are an SIRT6 small-molecule allosteric activator and the application thereof and provided is an SIRT6 small-molecule allosteric activator that contains a derivative as shown in formula (1) or a pharmacologically acceptable salt thereof as the active ingredient. The SIRT6 small-molecule allosteric activator designed and synthesized in the present invention has high efficacy and low toxicity, may significantly activate SIRT6 activity during in vitro experiments, and has great importance in the development of pharmaceuticals for relevant diseases.


Find Patent Forward Citations

Loading…