The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
Sep. 26, 2019
Xiamen University, Fujian, CN;
Xiamen Innovax Biotech Co., Ltd., Fujian, CN;
Shaowei Li, Fujian, CN;
Daning Wang, Fujian, CN;
Jie Chen, Fujian, CN;
Ying Gu, Fujian, CN;
Jun Zhang, Fujian, CN;
Ningshao Xia, Fujian, CN;
XIAMEN UNIVERSITY, Fujian, CN;
XIAMEN INNOVAX BIOTECH CO., LTD., Fujian, CN;
Abstract
Provided are a mutated HPV51 L1 protein or a variant thereof, a coding sequence thereof, a preparation method therefor, and a virus-like particle containing same, wherein the protein or the variant and the virus-like particle thereof are capable of inducing neutralizing antibodies against at least two types of HPV (for example, HPV51 and HPV69, or HPV51, HPV69 and HPV26). Also provided is the use of the above-mentioned protein and the virus-like particle for preparing a pharmaceutical composition or a vaccine, wherein the pharmaceutical composition or the vaccine can be used to prevent infections of the at least two types of HPV and diseases caused by the infections, such as cervical cancer and condyloma acuminatum.