The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
Apr. 15, 2022
Bristol-myers Squibb Company, Princeton, NJ (US);
Gene M. Dubowchik, Middlefield, CT (US);
Olafur S. Gudmundsson, West Windsor, NJ (US);
Xiaojun Han, Cheshire, CT (US);
R. Michael Lawrence, Yardley, PA (US);
Dasa Lipovsek, Pepperell, MA (US);
Cort S. Madsen, West Windsor, NJ (US);
Claudio Mapelli, Linden, NJ (US);
Paul E. Morin, Pennington, NJ (US);
Michael C. Myers, Newtown, PA (US);
BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);
Abstract
The present disclosure generally relates to modified relaxin polypeptides, such as modified human relaxin 2 polypeptides, comprising a non-naturally encoded amino acid which is linked to a pharmacokinetic enhancer, and therapeutic uses of such polypeptides, such as for the treatment of cardiovascular conditions (such as heart failure) and/or conditions relating to fibrosis.