The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
Sep. 10, 2019
Legend Biotech Ireland Limited, Dublin, IE;
Wang Zhang, Jiangsu, CN;
Yunlei Liu, Jiangsu, CN;
Xiaojie Tu, Jiangsu, CN;
Chenyu Shu, Jiangsu, CN;
Tailan Zhan, Jiangsu, CN;
Yun Zhang, Jiangsu, CN;
An Tang, Jiangsu, CN;
Yafeng Zhang, Jiangsu, CN;
Shu Wu, Jiangsu, CN;
Qing Zhang, Jiangsu, CN;
Legend Biotech Ireland Limited, Dublin, IE;
Abstract
Provided are single-domain antibodies targeting CLL1 and constructs thereof, including chimeric receptors, immune effector cell engagers and immunoconjugates. Further provided are engineered immune effector cells (such as T cells) comprising an anti-CLL1 chimeric receptor and optionally a second chimeric receptor targeting a second antigen or epitope. Pharmaceutical compositions, kits and methods of treating cancer are also provided.