The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2024

Filed:

Dec. 09, 2019
Applicants:

Ascentage Pharma (Suzhou) Co., Ltd., Suzhou, CN;

Ascentage Pharma Group Corp Limited, Hong Kong, CN;

Guangzhou Healthquest Pharma Co., Ltd., Guangdong, CN;

Inventors:

Yanqiong Lin, Suzhou, CN;

Jianfeng Wen, Suzhou, CN;

Feng Xu, Suzhou, CN;

Jiaan Huang, Suzhou, CN;

Shixiong Li, Suzhou, CN;

Xiaoling He, Suzhou, CN;

Shihe Liang, Suzhou, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 9/2054 (2013.01); A61K 9/4866 (2013.01);
Abstract

The present invention relates to a pharmaceutical composition containing alkynyl compound, a preparation method thereof and its application. The present invention discloses a pharmaceutical composition comprising an active pharmaceutical ingredient and an available pharmaceutical excipient; The active pharmaceutical ingredient is 3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-benzamide, or its pharmaceutical acceptable salt; The available pharmaceutical excipients includes diluents and lubricants. The pharmaceutical composition can effectively improve the bioavailability of the alkynyl compound, has good dissolution and stability, and improve the drug safety.


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