The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2024
Filed:
Feb. 24, 2022
Applicants:
The Children's Medical Center Corporation, Boston, MA (US);
Dompe Farmaceutici S.p.a., Milan, IT;
Inventors:
Paolo Fiorina, Boston, MA (US);
Roberto Bassi, Boston, MA (US);
Andrea Vergani, Brookline, MA (US);
Marcello Allegretti, Rome, IT;
Assignees:
THE CHILDREN'S MEDICAL CENTER CORPORATION, Boston, MA (US);
DOMPE FARMACEUTICI S.P.A., Milan, IT;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/18 (2006.01); A61K 31/426 (2006.01); A61K 45/06 (2006.01); A61P 3/10 (2006.01); A61P 13/12 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 31/18 (2013.01); A61K 31/426 (2013.01); A61K 45/06 (2013.01); A61P 3/10 (2018.01); A61P 13/12 (2018.01); G01N 33/68 (2013.01);
Abstract
Embodiments herein disclose methods relating to diabetic nephropathy (DN); methods for preventing the onset and also for preventing the progressing of DN, as well as the treatment of DN in diabetic subjects comprising administering reparixin and/or ladarixin which are inhibitors of CXCL8 receptor CXCR1 and CXCR2 activation.