The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2024
Filed:
Apr. 03, 2020
Applicant:
City University of Hong Kong, Kowloon, HK;
Inventors:
Youngjin Lee, Seoul, KR;
Abhimanyu Thakur, West Bengal, IN;
Chi-Man Lawrence Wu, Kowloon, HK;
Chen Xu, Nantong, CN;
Siu-Pang Ng, Kowloon, HK;
Assignee:
City University of Hong Kong, Kowloon, HK;
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); B01L 3/00 (2006.01); C07K 16/22 (2006.01); C07K 16/28 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/543 (2013.01); B01L 3/502 (2013.01); C07K 16/22 (2013.01); C07K 16/2884 (2013.01); C07K 16/2896 (2013.01); G01N 33/57488 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0803 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/12 (2013.01); B01L 2400/0484 (2013.01);
Abstract
A sensor for liquid biopsy, its method of making, and its method of non-invasive use. The sensor includes a substrate with a surface functionalized with biotinylated antibodies. The biotinylated antibodies are arranged to engage with surface proteins on exosomes associated with malignant cancer cells such as glioma cells.