The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2024
Filed:
Oct. 15, 2020
Applicants:
Taipei Veterans General Hospital, Taipei, TW;
National Chiao Tung University, Hsinchu, TW;
National Cheng Kung University, Tainan, TW;
Inventors:
Shih-Hwa Chiou, Taipei, TW;
Tien-Chun Yang, Taipei, TW;
Chia-Ching Chang, Hsinchu, TW;
Yon-Hua Tzeng, Tainan, TW;
Assignees:
Taipei Veterans General Hospital, Taipei, TW;
National Chiao Tung University, Hsinchu, TW;
National Cheng Kung University, Tainan, TW;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/90 (2006.01); A61K 9/51 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); A61K 9/5115 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract
The present invention provides a carboxylated nanodiamond-mediated CRISPR-Cas9 delivery system for gene editing comprising nanodiamond (ND) particles as the carriers of CRISPR-Cas9 components designed to introduce the mutation in a given gene for repairing a tissue damage.