The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2024
Filed:
Dec. 11, 2020
Applicant:
Element Biosciences, Inc., San Diego, CA (US);
Inventors:
Matthew Kellinger, San Diego, CA (US);
Molly He, San Diego, CA (US);
Tyler Lopez, San Diego, CA (US);
Assignee:
ELEMENT BIOSCIENCES, INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12N 9/12 (2006.01); C12P 21/00 (2006.01); C12Q 1/6874 (2018.01);
U.S. Cl.
CPC ...
C12N 15/102 (2013.01); C12N 9/1276 (2013.01); C12N 15/1068 (2013.01); C12Q 1/6874 (2013.01); C12Y 207/07049 (2013.01); C12N 2310/321 (2013.01); C12P 21/00 (2013.01);
Abstract
Provided herein are compositions and methods for the incorporation of unnatural nucleotides using mutant polymerases, such as reverse transcriptases. Further provided herein are methods of detection and sequencing of polynucleotide sequences. In some aspects, the compositions and methods are used enhance the efficiency and speed of detecting nucleotide bases. The methods and compositions described herein may further reduce time, cost, or scale of devices for next generation sequencing platforms.