The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2024

Filed:

Aug. 15, 2023
Applicant:

Omeros Corporation, Seattle, WA (US);

Inventors:

Thomas Dudler, Seattle, WA (US);

Peter Kurt Nollert von Specht, Seattle, WA (US);

Munehisa Yabuki, Seattle, WA (US);

Sadam Yaseen, Seattle, WA (US);

Assignee:

Omeros Corporation, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61P 3/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61P 3/00 (2018.01); C07K 2317/24 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01);
Abstract

Isolated monoclonal antibodies and antigen-binding fragments thereof are provided that specifically bind to an epitope within the serine protease domain of human MASP-2. In some embodiments, the antibodies or antigen-binding fragments thereof inhibit lectin pathway complement activation. Also provided are polynucleotides encoding the disclosed monoclonal antibodies or antigen-binding fragments thereof, and cloning vectors or expression cassettes comprising such polynucleotides. Further provided are methods of inhibiting lectin pathway complement activation and methods of treating lectin pathway diseases and disorders.


Find Patent Forward Citations

Dudler, Thomas. (2024). Therapeutic antibodies that bind to the serine protease domain of masp-2 and uses thereof (U.S. Patent No. 12091468). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12091468

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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