The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2024
Filed:
Jul. 02, 2021
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Shiro Shibayama, Ibaraki, JP;
Takuya Shimbo, Ibaraki, JP;
Tomoya Tezuka, Ibaraki, JP;
Mark Throsby, Utrecht, NL;
Cornelis Adriaan de Kruif, Utrecht, NL;
Pieter Fokko van Loo, Utrecht, NL;
Rinse Klooster, Utrecht, NL;
ONO PHARMACEUTICAL CO., LTD., Osaka, JP;
Abstract
A bispecific antibody which is capable of specifically binding to PD-1 and CD3 is disclosed. The bispecific antibody is suitable for preventing, suppressing symptom progression or recurrence of, and/or treating autoimmune diseases. Also disclosed is a formulation which can reduce occurrence of adverse infusion reactions or adverse reaction called cytokine release syndrome. The bispecific antibody has the feature to allow interaction between PD-1 and PD-L1 as its ligand, contributes enhancement or duration of its effects.