The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2024
Filed:
Oct. 14, 2021
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
David Karl Bedke, North Attleboro, MA (US);
Michael W. Gribble, Jr., Somerville, MA (US);
Michael G. Johnson, San Francisco, CA (US);
Todd J. Kohn, Thousand Oaks, CA (US);
Kexue Li, Newbury Park, CA (US);
Assignee:
AMGEN INC., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/10 (2006.01); C07D 513/20 (2006.01); C07D 515/10 (2006.01);
U.S. Cl.
CPC ...
C07D 513/10 (2013.01); C07D 513/20 (2013.01); C07D 515/10 (2013.01);
Abstract
Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.