The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2024
Filed:
May. 13, 2022
Albireo Ab, Gothenburg, SE;
Robert Lundqvist, Hälsö, SE;
Ingvar Ymen, Saltsjo-boo, SE;
Martin Bohlin, Johanneshov, SE;
Eva Byröd, Mölndal, SE;
Per-Göran Gillberg, Mölndal, SE;
Anna-Maria Tivert, Gothenburg, SE;
Rikard Bryland, Limhamn, SE;
Jessica Elversson, Dalby, SE;
Nils Ove Gustafsson, Löddeköpinge, SE;
Ann-Charlotte Dahlquist, Lund, SE;
Albireo AB, Gothenburg, SE;
Abstract
The present invention relates to crystal modifications of 1,1-dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-(N—{(R)-α-[N—((S)-1-carboxypropyl)carbamoyl]-4-hydroxybenzyl}carbamoylmethoxy)-2,3,4,5-tetrahydro-1,2,5-benzothiadiazepine (odevixibat), more specifically crystal modifications 1 and 2 of odevixibat. The invention also relates to a process for the preparation of crystal modification 1 of odevixibat, to a pharmaceutical composition comprising crystal modification 1, and to the use of this crystal modification in the treatment of various conditions as described herein.