The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2024

Filed:

Sep. 14, 2018
Applicants:

Riken, Wako, JP;

Sumitomo Pharma Co., Ltd., Osaka, JP;

Inventors:

Daiki Nukaya, Tokyo, JP;

Mototsugu Eiraku, Wako, JP;

Yuiko Kinose, Wako, JP;

Akishi Onishi, Wako, JP;

Masayo Takahashi, Wako, JP;

Yoshiki SASAI, Wako, JP;

Assignees:

RIKEN, Wako, JP;

SUMITOMO PHARMA CO., LTD., Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/38 (2006.01); C12N 5/0793 (2010.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3895 (2013.01); A61L 27/3891 (2013.01); C12N 5/062 (2013.01); G01N 33/5088 (2013.01); A61L 2430/16 (2013.01); A61L 2430/32 (2013.01); C12N 2501/155 (2013.01); C12N 2501/395 (2013.01); C12N 2501/999 (2013.01);
Abstract

The present invention aims to provide a method for suppressing differentiation of ganglion cell, amacrine cell, horizontal cell and/or bipolar cell in a neural retina tissue containing photoreceptor precursor and/or photoreceptor, and the like. A method for suppressing differentiation of a ganglion cell, an amacrine cell, a horizontal cell and/or a bipolar cell in a neural retinal tissue containing a photoreceptor precursor and/or a photoreceptor, including a step of culturing a retinal tissue comprising a neural retinal progenitor cell and in any stage between a differentiation stage immediately after emergence of a ganglion cell and a differentiation stage where emergence rate of a cone photoreceptor precursor reaches maximum in a medium containing a thyroid gland hormone signal transduction pathway agonist.


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