The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2024
Filed:
Nov. 21, 2022
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Thomas Pillow, South San Francisco, CA (US);
Peter Dragovich, South San Francisco, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 47/65 (2017.01); C07K 16/22 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6803 (2017.08); A61K 47/65 (2017.08); A61K 47/6889 (2017.08); C07K 16/22 (2013.01); C07K 16/2863 (2013.01);
Abstract
The subject matter described herein is directed to methods of preparing certain antibody-drug conjugates (ADCs) wherein the antibody is linked to the drug through a linker, wherein the drug contains a heteroaryl group having a secondary nitrogen, and the linker is attached to the drug via the secondary nitrogen. The resulting conjugates are useful in treating various diseases and conditions.