The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2024
Filed:
Nov. 19, 2018
Applicant:
Keio University, Tokyo, JP;
Inventors:
Masahiro Toda, Tokyo, JP;
Hideyuki Okano, Tokyo, JP;
Hiroyuki Miyoshi, Tokyo, JP;
Ryota Tamura, Tokyo, JP;
Assignee:
KEIO UNIVERSITY, Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/30 (2015.01); A61K 31/513 (2006.01); A61P 35/00 (2006.01); C12N 5/0797 (2010.01); C12N 9/10 (2006.01); C12N 9/78 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
A61K 35/30 (2013.01); A61K 31/513 (2013.01); A61P 35/00 (2018.01); C12N 5/0623 (2013.01); C12N 9/1077 (2013.01); C12N 9/78 (2013.01); C12N 15/635 (2013.01); C12Y 204/02009 (2013.01); C12Y 305/04001 (2013.01); C12N 2506/45 (2013.01);
Abstract
A cell preparation for treating brain tumors used in combination with a prodrug that is converted to 5-fluorouracil by cytosine deaminase, wherein the cell preparation comprises neural stem cells derived from pluripotent stem cells having a cytosine deaminase gene and a uracil phosphoribosyltransferase gene is provided to establish new means for treating brain tumors.