The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2024
Filed:
Nov. 03, 2018
Applicant:
Dsm Nutritional Products, Llc, Parsippany, NJ (US);
Inventors:
Molly Krisann Gibson, Medford, MA (US);
Nathan Wilson Stebbins, Cambridge, MA (US);
Ruth Thieroff-Ekerdt, Concord, MA (US);
Geoffrey A. von Maltzahn, Boston, MA (US);
Assignee:
DSM Nutritional Products, LLC, Parsippany, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/716 (2006.01); A61K 35/741 (2015.01); A61K 47/10 (2017.01); A61P 3/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/716 (2013.01); A61K 35/741 (2013.01); A61K 47/10 (2013.01); A61P 3/12 (2018.01);
Abstract
Compositions, e.g., pharmaceutical compositions, nutritional compositions, medical foods, and food ingredients, as well as their methods of use, are provided, for treating diseases associated with hyperammonemia, e.g., urea cycle disorders (UCD) and hepatic encephalopathy (HE), e.g., minimal HE (MHE) and overt HE (OHE), and modulating enzyme activities and levels of microbes and taxa, and metabolites (e.g., ammonia) in the microbiome of a subject.