The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2024
Filed:
Feb. 15, 2023
Applicant:
Institute of Ophthalmology Affiliated to Shandong First Medical University (Shandong Institute of, Qingdao, CN;
Inventors:
Weiyun Shi, Qingdao, CN;
Qingjun Zhou, Qingdao, CN;
Hongwei Wang, Qingdao, CN;
Bining Zhang, Qingdao, CN;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); A61K 9/06 (2006.01); A61K 9/127 (2006.01); A61K 47/24 (2006.01); A61K 47/28 (2006.01); A61K 47/42 (2017.01); A61P 27/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/501 (2013.01); A61K 9/06 (2013.01); A61K 9/127 (2013.01); A61K 47/24 (2013.01); A61K 47/28 (2013.01); A61K 47/42 (2013.01); A61P 27/02 (2018.01);
Abstract
In view of the problem that the current prevention and treatment manners for corneal neovascularization (CNV) may cause complications, the present disclosure provides an application of CB-839 in preparation of a drug for inhibiting CNV. The CB-839-loaded drug of the present disclosure can significantly inhibit CNV in mice and reduce the infiltration of inflammatory cells without obvious side effects, which makes up for the shortcoming of the prior art.