The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2024

Filed:

Sep. 20, 2019
Applicant:

Bionomics Limited, Eastwood, AU;

Inventors:

Hamish Toop, Eastwood, AU;

Rajinder Singh, Eastwood, AU;

Erin Smith, Eastwood, AU;

Dharam Paul, Eastwood, AU;

Patrick Bazzini, Strasbourg, FR;

Jean-Marie Contreras, Westhouse, FR;

Christophe Morice, Widensolen, FR;

Florence Chery, Strasbourg, FR;

Fabrice Garrido, Illkirch, FR;

Assignee:

Bionomics Limited, Eastwood, AU;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61P 25/18 (2006.01); A61P 25/28 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); C07D 401/04 (2013.01); A61P 25/18 (2018.01); A61P 25/28 (2018.01);
Abstract

The present application relates generally to compounds useful for the treatment and/or enhancement of cognitive dysfunction and negative symptoms associated with CNS disorders where the circuitry involving fast spiking PV+ interneurons and the production of cortical gamma oscillations is disrupted. The subject disclosure enables the manufacture of medicaments as well as compositions containing same for use in methods of therapy and prophylaxis of cognitive dysfunction and negative symptoms.


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