The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2024
Filed:
Jun. 21, 2019
MD Healthcare Inc., Seoul, KR;
Yoon-Keun Kim, Gyeonggi-do, KR;
MD HEALTHCARE INC., Seoul, KR;
Abstract
The present invention relates to a method for prognosing the occurrence and the causative factor of an inflammatory bowel disease such as ulcerative colitis and Crohn's disease by means of a metagenomic analysis of bacterial and bacterial-derived vesicles present in a human body-derived substance and, more particularly, to a method for diagnosing the causative factor and occurrence risk of an inflammatory bowel disease by analyzing a metagenomic sequence present in bacteria and bacteria-derived vesicles present in stool. Trillions of bacteria are present in the intestine, and vesicles are secreted outside the cells for exchange of information. Bacterial are not absorbed into the intestinal epithelial cells, but the vesicles secreted from the bacteria pass through the mucous, are absorbed into the intestinal epithelial cells and can increase or reduce inflammation. The present invention can be facilitated as a method for diagnosing the occurrence risk and causative factor of an inflammatory bowel disease by means of a gene metagenomic sequence analysis of bacteria and bacterial=-derived vesicles present in a human body-derived substance. Also, the present invention enables early diagnosis even after an occurrence of an inflammatory bowel disease, reduces the occurrence of an inflammatory bowel disease, and can enhance therapeutic effects.