The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2024
Filed:
May. 17, 2022
Applicant:
Translate Bio, Inc., Waltham, MA (US);
Inventors:
Frank DeRosa, Cambridge, MA (US);
Anusha Dias, Cambridge, MA (US);
Michael Heartlein, Cambridge, MA (US);
Assignee:
TRANSLATE BIO, INC., Waltham, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C07K 14/505 (2006.01); C12N 9/02 (2006.01); C12Q 1/6823 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/68 (2013.01); C07K 14/505 (2013.01); C12N 9/0069 (2013.01); C12Q 1/6823 (2013.01); C12Y 113/12007 (2013.01);
Abstract
The present invention provides, among other things, methods of quantitating mRNA capping efficiency, particularly for mRNA synthesized in vitro. In some embodiments, the methods comprise chromatographic methods of quantifying capping efficiency and methylation status of the caps.