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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12084692 B1

PDFFull Text
Date of Patent:
Sep. 10, 2024

Filed:

Nov. 22, 2022

Guide scaffolds

Applicant:

Scribe Therapeutics Inc., Alameda, CA (US);

Inventors:

Benjamin Oakes, El Cerrito, CA (US);

Sean Higgins, Alameda, CA (US);

Hannah Spinner, Boston, MA (US);

Sarah Denny, San Francisco, CA (US);

Brett T. Staahl, Tiburon, CA (US);

Kian Taylor, Atlanta, GA (US);

Katherine Baney, Berkeley, CA (US);

Isabel Colin, Oakland, CA (US);

Maroof Adil, Davis, CA (US);

Assignee:

Scribe Therapeutics Inc., Alameda, CA (US);

Attorney:

Cooley LLP

Primary Examiner:

Nancy J Leith

Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/86 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/86 (2013.01); C12N 15/907 (2013.01); C12N 2310/20 (2017.05); C12N 2740/15043 (2013.01);
Abstract

Provided herein are reference guide nucleic acid scaffolds and variants of reference guide nucleic acid scaffolds capable of binding one or more engineered proteins comprising a RuvC cleavage domain. In some embodiments, the variants of the reference guide nucleic acid scaffolds comprise at least one modification compared to the reference guide nucleic acid scaffold sequences and exhibit one or more improved characteristics compared to the reference guide nucleic acid scaffolds.

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Oakes, Benjamin. (2024). Guide scaffolds (U.S. Patent No. 12084692). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12084692

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