The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2024
Filed:
Jan. 05, 2023
Applicant:
22nd Century Limited, Llc, Buffalo, NY (US);
Inventors:
Takashi Hashimoto, Ikoma, JP;
Akira Kato, Nara, JP;
Assignee:
22nd Century Limited, LLC, Buffalo, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); A24B 13/00 (2006.01); A24B 15/10 (2006.01); A61K 31/455 (2006.01); C12N 9/02 (2006.01); C12N 9/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8218 (2013.01); A24B 13/00 (2013.01); A24B 15/10 (2013.01); A61K 31/455 (2013.01); C12N 9/0004 (2013.01); C12N 9/0012 (2013.01); C12N 9/0022 (2013.01); C12N 15/8216 (2013.01); C12N 15/8243 (2013.01); C12N 15/8279 (2013.01); C12N 15/8286 (2013.01); C12Y 104/03006 (2013.01); Y02A 40/146 (2018.01);
Abstract
MPO1 and MPO2 can be regulated for either decreasing or increasing alkaloid levels in plants, in particular inplants. In particular, suppressing or overexpressing one or more of MPO1 and MPO2 may be used to decrease or increase nicotine and nicotinic alkaloid levels in tobacco plants. Suppression or overexpression of one or more of MPO1 and MPO2 may be used in combination with modification of expression of other genes encoding enzymes on the nicotinic alkaloid biosynthetic pathway such as A622, NBB1, PMT, and QPT.