The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2024
Filed:
Apr. 13, 2022
Applicant:
Dicerna Pharmaceuticals, Inc., Lexington, MA (US);
Inventors:
Utsav Saxena, Watertown, MA (US);
Henryk T. Dudek, Belmont, MA (US);
Marc Abrams, Natick, MA (US);
Anton Turanov, Revere, MA (US);
Bob Dale Brown, Littleton, MA (US);
Assignee:
Dicerna Pharmaceuticals, Inc., Lexington, MA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/7125 (2006.01); C07H 21/02 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 31/7125 (2013.01); C07H 21/02 (2013.01); C12N 2310/315 (2013.01); C12N 2310/32 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3515 (2013.01); C12P 19/34 (2013.01);
Abstract
Oligonucleotides and compositions including the same are disclosed for inhibiting or reducing patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene expression. Methods of making and using the oligonucleotides also are disclosed, particularly uses relating to treating diseases, disorders and/or conditions associated with PNPLA3 expression.