The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2024
Filed:
Feb. 21, 2020
Gilead Sciences, Inc., Foster City, CA (US);
National Research Council of Canada, Ottawa, CA;
Ilia Alexandre Tikhomirov, Toronto, CA;
Maria L. Jaramillo, Beaconsfield, CA;
Maureen D. O'Connor-McCourt, Beaconsfield, CA;
Traian Sulea, Kirkland, CA;
Renald Gilbert, Montreal, CA;
Bruno Gaillet, Sainte Julienne, CA;
Jason Baardsnes, Montreal, CA;
Myriam Banville, Laval, CA;
Suzanne Grothe, Montreal, CA;
Gilead Sciences, Inc., Foster City, CA (US);
National Research Council of Canada, Ottawa, CA;
Abstract
Herein described are antibodies to epidermal growth factor receptor (EGER) having an EGER binding affinity that is sufficient to kill disease cells presenting EGFR at high density, but is insufficient for binding to normal cells. A therapeutic effect is thus achieved while avoiding adverse events that result from unintended binding to normal cells.