The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2024
Filed:
Sep. 16, 2022
Vib Vzw, Ghent, BE;
Vrije Universiteit Brussel, Brussels, BE;
Oxford Nanopore Technologies Plc, Oxford, GB;
Han Remaut, Ghent, BE;
Sander Egbert Van Der Verren, Serskamp, BE;
Nani Van Gerven, Huizingen, BE;
Lakmal Nishantha Jayasinghe, Oxford, GB;
Elizabeth Jayne Wallace, Oxford, GB;
Pratik Raj Singh, Oxford, GB;
Richard George Hambley, Oxford, GB;
Michael Robert Jordan, Oxford, GB;
John Joseph Kilgour, Oxford, GB;
VIB VZW, Ghent, BE;
Vrije Universiteit Brussel, Brussels, BE;
Oxford Nanopore Technologies PLC, Oxford, GB;
Abstract
The present invention relates to novel protein pores and their uses in analyte detection and characterisation. The invention particularly relates to an isolated pore complex formed by a CsgG-like pore and a modified CsgF peptide, or a homologue or mutant thereof, thereby incorporating an additional channel constriction or reader head in the nanopore. The invention further relates to a transmembrane pore complex and methods for production of the pore complex and for use in molecular sensing and nucleic acid sequencing applications.