The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2024

Filed:

Nov. 29, 2021
Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Patrick Rene Angibaud, Saint Pierre d'Autils, FR;

Vineet Pande, Vosselaar, BE;

Barbara Herkert, Flonheim, DE;

Daniel Jason Krosky, Blue Bell, PA (US);

Olivier Alexis Georges Querolle, Saint Vigor, FR;

Aaron Nathaniel Patrick, Doylestown, PA (US);

Isabelle Noelle Constance Pilatte, Louviers, FR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01);
Abstract

The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to spiro bicyclic compounds, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes.


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