The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2024
Filed:
Nov. 03, 2023
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Stephan Bachmann, Allschwil, CH;
Lukas Chytil, Grellingen, CH;
Serena Maria Fantasia, Saint-Louis, FR;
Alec Fettes, Hagendorn, CH;
Ursula Hoffmann, Muttenz, CH;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); B01J 21/18 (2006.01); B01J 23/648 (2006.01); B01J 31/22 (2006.01); B01J 31/24 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); B01J 21/18 (2013.01); B01J 23/6482 (2013.01); B01J 31/2256 (2013.01); B01J 31/2265 (2013.01); B01J 31/2404 (2013.01); C07D 401/04 (2013.01); B01J 2231/4211 (2013.01); B01J 2531/824 (2013.01);
Abstract
Methods for preparing the Bruton's Tyrosine Kinase ('BTK') inhibitor compound 2-{3'-hydroxymethyl-1-methyl-5-[5-((S)-2-methyl-4-oxetan-3-yl-piperazin-1-yl)-pyridin-2-ylamino]-6-oxo-1,6-dihydro-[3,4′]bipyridinyl-2′-yl}-7,7-dimethyl-3,4,7,8-tetrahydro-2H,6H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1-one are provided.