The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2024
Filed:
Aug. 31, 2023
Incyte Corporation, Wilmington, DE (US);
Jiacheng Zhou, Newark, DE (US);
Zhongjiang Jia, Kennett Square, PA (US);
Qiyan Lin, Newark, DE (US);
Pingli Liu, Wilmington, DE (US);
Yongchun Pan, Wilmington, DE (US);
Timothy Martin, Hockessin, DE (US);
Bo Shen, Garnet Valley, PA (US);
Naijing Su, Hockessin, DE (US);
Yongzhong Wu, Glen Mills, PA (US);
Incyte Corporation, Wilmington, DE (US);
Abstract
The present invention relates to processes of preparing PD-1/PD-L1 inhibitor (R)-1-((7-cyano-2-(3'-(3-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-1,7-naphthyridin-8-ylamino)-2,2′-dimethylbiphenyl-3-yl)benzo[d]oxazol-5-yl)methyl)pyrrolidine-3-carboxylic acid, or salts thereof, related synthetic intermediates, and salts of the intermediates, where the PD-1/PD-L1 inhibitor is useful in the treatment of various diseases including infectious diseases and cancer.